Stop treating enterprise sales like a numbers game. A successful account-based outbound strategy is an infrastructure problem, not a volume problem.
Enterprise deals require buy-in from multiple stakeholders. Your strategy must focus on account-level penetration, not just lead replies.
Blasting multiple contacts at a target firm from one domain is a fast way to get your entire company blacklisted. Use domain pools.
An account-based outbound strategy fails without infrastructure to coordinate multi-channel touches across the entire buying committee.
Your CRM manages relationships. A dedicated outbound platform manages the sending infrastructure needed to start those relationships at scale.
Most sales teams approach account-based marketing by simply sending more emails to more contacts at their target accounts. They buy bigger lists, increase the number of sequence steps, and push their SDRs to hit higher activity metrics. This was a plausible strategy in 2018.
In 2025, this approach is a guaranteed way to get your domain blacklisted. Enterprise buying committees are larger, spam filters are more aggressive, and decision-makers are numb to generic, high-volume outreach. Blasting multiple contacts at the same company from a single domain is a signal of low-quality sending that email providers are actively penalizing.
Winning enterprise deals requires a shift in mindset: from volume to coordinated penetration. This isn't about sending more emails; it's about landing the right messages in front of the right personas across the buying committee at the right time. And that is fundamentally an infrastructure problem.
The traditional approach to outbound is built on a fragile foundation. A team uses their primary corporate domain (e.g., acme.com) or a single variation (acmecorp.com) for all outreach. Every SDR sends from their personal inbox, managed inside a CRM or a simple mail merge tool.
This breaks instantly when applied to an account-based strategy for a few reasons:
A modern account-based strategy treats sending infrastructure as a core part of the GTM motion. The goal is no longer just 'more activity,' but 'safe, coordinated, and effective penetration' of target accounts. This requires a dedicated, isolated, and intelligently managed setup.
Here are the core components:
acme-solutions.com, acme-group.com). These are used exclusively for outbound and are isolated from your corporate domain. Inboxes are created on these domains and warmed up over weeks before ever sending a cold email.Transitioning to an infrastructure-first model doesn't happen overnight. It's a phased process that prioritizes stability and effectiveness over raw speed.
Phase 1: Build and Warm Your Infrastructure.
Before you contact a single account, build your foundation. Purchase 5-10 dedicated outbound domains. Set up 10-20 inboxes across them. Configure SPF, DKIM, and DMARC correctly for each one. Put every single inbox on an automated warmup schedule using a tool like SuperSend. Do not send a cold email for at least 4-6 weeks. This step is non-negotiable.
Phase 2: Map Accounts and Sequences.
While your infrastructure warms, do the strategic work. Build your target account list. Identify the 3-5 key personas that make up the buying committee. Develop multi-channel sequences tailored to each persona, with steps that reference the account's specific challenges. Design the logic for how these sequences will interact (e.g., don't email two VPs on the same day).
Phase 3: Execute, Measure, and Optimize.
Begin sending to a small cohort of your target accounts. The goal here is not to measure individual reply rates, but account penetration. Are multiple contacts at the company opening your emails? Are you getting replies from different departments? Are you booking meetings with the right people? Your core KPI is meetings booked with qualified accounts, not vanity metrics like open rates.
You cannot run this strategy from your CRM. A CRM is a database for managing relationships, not an execution engine for managing complex sending infrastructure. Its sending capabilities are an afterthought, and using them for cold outbound is a great way to destroy your primary domain's reputation.
Likewise, simple Gmail plugins lack the sophistication to rotate domains, manage warmup pools, and orchestrate multi-channel sequences at an account level. They are designed for individual users, not for a coordinated team strategy.
SuperSend is built as the dedicated outbound execution and infra layer that sits alongside your CRM and data tools. It manages the entire lifecycle of your domains and inboxes, from warmup to rotation, and executes coordinated multi-channel sequences at scale.
Understanding how to structure these sequences is the next logical step. You can see proven patterns and templates for engaging enterprise accounts in our sequence library.
Join thousands of teams using SuperSend to transform their cold email campaigns and drive more revenue.